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Cyclodextrin role

2020-01-18 17:07:28 Xinda Biotechinology Read

1, the role of inclusion
Since the internal cavity of the cyclodextrin is, we can put a variety of organic molecules inhaled them. This phenomenon is called "inclusion."
※ inclusion process water is necessary.
We called the general cyclodextrin inclusion body is an inclusion of the substance is called inclusion bodies. We said cyclodextrin molecule structure like a bucket without a lid and conical bottom, but because of inclusion body and the body is wrapped with a variety of connection between each other gravitationally, or by inclusion in the body after being very inclusion difficult to separate out again. Cyclodextrins are nanoscale capsules, also known as the world's smallest capsules.
2, sustained release
Being inside the cyclodextrin inclusion body, nor is it fixed under certain conditions will be gradually released. Molecular process a little release, we call it "sustained release."
 ※ sustained process of water is necessary.
For example, cyclodextrins can be spicy and flavor, and so the active ingredients inclusion, and then slowly released, so the flavor can be stored for a long time and use.
3, stability role
Some of the ultraviolet light, heat sensitive unstable substance can be achieved through the inclusion of stability. That is, the cyclodextrin those ultraviolet rays, heat sensitive, easy to acidification, water easily decomposed substances through inclusion wherein the active ingredient can be stabilized to prevent deterioration and improve storage stability.
4, to improve the utilization of biological
Many well-known substance is an active ingredient molecules accumulate together. Since the state of the cyclodextrin inner diameter of the capsule 1 nm or less, when the inclusion of active ingredients, can effectively cut off the intermolecular attraction of the particles to achieve, after the active ingredient into particles, we can increase the effective ingredient in vivo absorbability and duration , improve the utilization of the biology.
For example, coenzyme Q10 kind of fat-soluble substances, when fasting is almost impossible to absorb in the body, but by γ-cyclodextrin inclusion, drink at any time, it can increase its absorption and persistence.
5, adjust the viscosity effect
For the inclusion of high-viscosity material to cut the cohesion between molecules, to reduce the viscosity effect.
6, deodorizing effect
After cyclodextrin inclusion odor and bitter taste, can reduce odor and bitter taste perception, improve our taste and smell.
7, anti-moisture effects
For easy deliquescence in the air, through the inclusion of cyclodextrin can suppress moisture absorption and deliquescence, to prevent moisture effect.
8, powdered effect
By inclusion, it can be unstable gases (such as carbon dioxide) and liquid (such as oil, spices, etc.) into a stable state of powder, to facilitate a variety of utilization.
9, dissolution
For some poorly water-soluble substances through inclusion can make material was dissolved. Especially for oily substances difficultly soluble in water, due to being a so-called cyclodextrin inclusion capsule after the capsule inner and outer capsules lipophilic hydrophilic, water-like substance can be dissolved in water dispersion, which It is dissolution.

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